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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628700
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fadd
Name: Fas associated via death domain
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Faddincreases expressionEXP 6480464CTDCholesterol results in increased expression of FADD proteinPMID:20946910
Faddmultiple interactionsEXP 6480464CTDCholesterol promotes the reaction [Hydrogen Peroxide results in increased expression of FADD protein]; Hydrogen Peroxide promotes the reaction [Cholesterol results in increased expression of FADD protein]PMID:20946910
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