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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628658
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bmf
Name: Bcl2 modifying factor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bmfaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of BMF mRNAPMID:22298810
Bmfdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of BMF mRNAPMID:21215274 PMID:33387578
Bmfincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of BMF mRNAPMID:32109520
Bmfmultiple interactionsEXP 6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of BMF mRNA]PMID:21215274
Bmfaffects expressionISOBMF (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of BMF mRNAPMID:22298810
Bmfaffects expressionISOBmf (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of BMF mRNAPMID:21570461 PMID:28922406
Bmfincreases expressionISOBMF (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of BMF mRNA; Tetrachlorodibenzodioxin results in increased expression of BMF proteinPMID:20106945 PMID:21632981 PMID:22903824 PMID:26159488 PMID:26238291 PMID:31536130
Bmfincreases expressionISOBmf (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BMF mRNAPMID:19770486 PMID:19933214 PMID:20819909 PMID:21889950
Bmfmultiple interactionsISOBMF (Homo sapiens)6480464CTDWWTR1 affects the reaction [Tetrachlorodibenzodioxin results in increased expression of BMF mRNA]; YAP1 affects the reaction [Tetrachlorodibenzodioxin results in increased expression of BMF mRNA]PMID:31536130
Bmfmultiple interactionsISOBmf (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of BMF mRNA; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to BMF gene]PMID:20819909 PMID:25975270
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