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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628627
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b3
Name: cytochrome P450, family 2, subfamily b, polypeptide 3
Acc ID: CHEBI:2607
Term: Aloe emodin
Definition: A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe.
Chemical ID: MESH:C518327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b3increases chemical synthesisISOCYP2B6 (Homo sapiens)6480464CTDCYP2B6 protein results in increased chemical synthesis of aloe emodinPMID:29698620
Cyp2b3multiple interactionsISOCYP2B6 (Homo sapiens)6480464CTD[CYP2B6 protein results in increased metabolism of chrysophanic acid] which results in increased chemical synthesis of aloe emodinPMID:29698620
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