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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628614
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Afm
Name: afamin
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Afmdecreases expressionEXP 6480464CTDDiethylnitrosamine results in decreased expression of AFM mRNAPMID:19638242
Afmmultiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AFM mRNAPMID:28943392
Afmincreases expressionISOAfm (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of AFM mRNAPMID:17942915
Afmmultiple interactionsISOAfm (Mus musculus)6480464CTDMET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AFM mRNA]PMID:17942915
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