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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62391
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:68233
Term: (Z)-3-butylidenephthalide
Definition: A gamma-lactone that is phthalide substituted by a butylidene group at position 3. Isolated from Ligusticum porteri, it exhibits hypoglycemic activity.
Chemical ID: MESH:C026105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3increases expressionISODDIT3 (Homo sapiens)6480464CTDbutylidenephthalide results in increased expression of DDIT3 proteinPMID:23770345
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