Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62387
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdx1
Name: pancreatic and duodenal homeobox 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdx1multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Dietary Fats results in decreased expression of PDX1 mRNA]; resveratrol inhibits the reaction [Dietary Fats results in decreased expression of PDX1 protein]PMID:25228148
Pdx1increases expressionISOPDX1 (Homo sapiens)6480464CTDresveratrol results in increased expression of PDX1 mRNAPMID:21163946
Pdx1increases expressionISOPdx1 (Mus musculus)6480464CTDresveratrol results in increased expression of PDX1 proteinPMID:24036142
Pdx1multiple interactionsISOPDX1 (Homo sapiens)6480464CTD6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [SIRT1 protein promotes the reaction [resveratrol results in increased expression of PDX1 mRNA]]; SIRT1 protein promotes the reaction [resveratrol results in increased expression of PDX1 mRNA]PMID:21163946
Go Back to source page   Continue to Ontology report