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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62373
Species: Mus musculus
RGD Object: Gene
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Acc ID: CHEBI:2981
Term: baicalin
Definition: The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.
Chemical ID: MESH:C038044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hes1increases expressionISOHES1 (Homo sapiens)6480464CTDbaicalin results in increased expression of HES1 mRNAPMID:19160421
Hes1multiple interactionsISOHES1 (Homo sapiens)6480464CTDN-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]PMID:19160421
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