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GENE - TERM ANNOTATION REPORT

RGD ID: 62329
Species: Mus musculus
RGD Object: Gene
Symbol: Arc
Name: activity regulated cytoskeletal-associated protein
Acc ID: DOID:0060001
Term: withdrawal disorder
Definition: A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Withdrawal "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arc IEP 401959609RGDassociated with morphine dependence; mRNA,protein:increased expression:brain (mouse) 
Arc ISOArc (Rattus norvegicus)401938601RGDassociated with morphine dependence;protein:increased expression:brain (rat) 
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