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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62287
Species: Mus musculus
RGD Object: Gene
Symbol: Pten
Name: phosphatase and tensin homolog
Acc ID: CHEBI:9747
Term: Triptolide
Definition: An oxacycle that has formula C20H24O6.
Chemical ID: MESH:C001899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptenincreases expressionEXP 6480464CTDtriptolide results in increased expression of PTEN proteinPMID:30394310
Ptenmultiple interactionsEXP 6480464CTDNOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of PTEN protein]PMID:30394310
Ptenincreases expressionISOPTEN (Homo sapiens)6480464CTDtriptolide results in increased expression of PTEN proteinPMID:30394310
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