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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621835
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Idi1
Name: isopentenyl-diphosphate delta isomerase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Idi1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of IDI1 mRNAPMID:16054898 PMID:21215274 PMID:32109520 PMID:33387578 PMID:34747641
Idi1affects expressionISOIdi1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of IDI1 mRNAPMID:28922406
Idi1decreases expressionISOIDI1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of IDI1 proteinPMID:31225620
Idi1decreases expressionISOIdi1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of IDI1 mRNAPMID:17337447 PMID:28238261
Idi1increases expressionISOIdi1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of IDI1 mRNAPMID:19465110
Idi1multiple interactionsISOIdi1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of IDI1 mRNAPMID:28433925
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