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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
Acc ID: CHEBI:9309
Term: N-succinylsulfathiazole
Definition: A 1,3-thiazole that has formula C13H13N3O5S2.
Chemical ID: MESH:C009342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit4increases expressionISODdit4 (Mus musculus)6480464CTDsuccinylsulfathiazole results in increased expression of DDIT4 proteinPMID:33957263
Ddit4multiple interactionsISODdit4 (Mus musculus)6480464CTD[Folic Acid deficiency co-treated with succinylsulfathiazole] results in decreased expression of DDIT4 proteinPMID:33957263
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