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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
Acc ID: CHEBI:33083
Term: fluoranthene
Definition: An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring.
Chemical ID: MESH:C007738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit4multiple interactionsISODdit4 (Mus musculus)6480464CTD[1-methylanthracene co-treated with fluoranthene] results in increased expression of DDIT4 mRNA; SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of DDIT4 mRNA]PMID:28329830
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