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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621673
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gli1
Name: GLI family zinc finger 1
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gli1increases expressionISOGLI1 (Homo sapiens)6480464CTDGlucose results in increased expression of GLI1 proteinPMID:33992720
Gli1multiple interactionsISOGli1 (Mus musculus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]PMID:27481074
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