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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621537
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabbr1
Name: gamma-aminobutyric acid type B receptor subunit 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabbr1multiple interactionsEXP 6480464CTD[Ozone co-treated with Chlorine] results in increased expression of GABBR1 mRNAPMID:18636392
Gabbr1decreases expressionISOGabbr1 (Mus musculus)6480464CTDOzone results in decreased expression of GABBR1 mRNAPMID:33026818
Gabbr1multiple interactionsISOGABBR1 (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of GABBR1 mRNA; [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of GABBR1 mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of GABBR1 mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased expression of GABBR1 mRNAPMID:32699268 PMID:32845096
Gabbr1multiple interactionsISOGabbr1 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of GABBR1 mRNAPMID:34911549
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