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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il11
Name: interleukin 11
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il11increases expressionEXP 6480464CTDAcetaminophen results in increased expression of IL11 mRNAPMID:33387578
Il11increases expressionISOIl11 (Mus musculus)6480464CTDAcetaminophen results in increased expression of IL11 mRNAPMID:11826401 PMID:12705907
Il11multiple interactionsISOIl11 (Mus musculus)6480464CTDIL10 protein inhibits the reaction [Acetaminophen results in increased expression of IL11 mRNA]; IL11 protein inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; IL6 protein affects the reaction [Acetaminophen results in increased expression of IL11 mRNA]PMID:11421492 PMID:11826401 PMID:12705907
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