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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621238
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf1b
Name: TNF receptor superfamily member 1B
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf1bmultiple interactionsISOTnfrsf1b (Mus musculus)6480464CTD[TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of PDGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of TGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] results in decreased susceptibility to Asbestos, SerpentinePMID:9846974
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