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GENE - TERM ANNOTATION REPORT

RGD ID: 621200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Elob
Name: elongin B
Acc ID: GO:0070449
Term: elongin complex
Definition: A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.
Definition Source(s): PMID:12676794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elobpart_ofISOELOB (Homo sapiens)1624291RGD PMID:7660122

PMID:7660122
Elobpart_ofISOElob (Mus musculus)1624291RGD MGI:5499725 PMID:16498413

MGI:5499725 PMID:16498413
Elobpart_ofIBAFB:FBgn0023212 or MGI:1914923 or PANTHER:PTN000997498 or UniProtKB:Q153701600115GO_CentralGO_REF:0000033

GO_REF:0000033
Elobpart_ofIEAInterPro:IPR0390491600115InterProGO_REF:0000002

GO_REF:0000002
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