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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ogg1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ogg1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of OGG1 mRNAPMID:16751229
Ogg1affects expressionISOOgg1 (Mus musculus)6480464CTDAcetaminophen affects the expression of OGG1 mRNAPMID:17562736
Ogg1increases expressionISOOGG1 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of OGG1 mRNAPMID:25704631 PMID:29067470
Ogg1increases expressionISOOgg1 (Mus musculus)6480464CTDAcetaminophen results in increased expression of OGG1 mRNAPMID:12540782
Ogg1multiple interactionsISOOgg1 (Mus musculus)6480464CTDO(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of OGG1 mRNA]PMID:12540782
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