Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621120
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk4
Name: cyclin-dependent kinase 4
Acc ID: CHEBI:65329
Term: LY294002
Definition: A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2.
Chemical ID: MESH:C085911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk4multiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CDK4 protein]; [kaempferol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Oxygen deficiency results in increased expression of CDK4 protein]PMID:36940862
Cdk4multiple interactionsISOCDK4 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDK4 protein]PMID:27312872
Go Back to source page   Continue to Ontology report