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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1decreases expressionEXP 6480464CTDtroglitazone results in decreased expression of COL1A1 mRNAPMID:16813520
Col1a1increases expressionEXP 6480464CTDtroglitazone results in increased expression of COL1A1 mRNAPMID:28973697
Col1a1affects expressionISOCol1a1 (Rattus norvegicus)6480464CTDtroglitazone affects the expression of COL1A1 mRNAPMID:15211114
Col1a1multiple interactionsISOCOL1A1 (Homo sapiens)6480464CTDtroglitazone inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]PMID:18253093
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