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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:6888
Term: 6alpha-methylprednisolone
Definition: The 6alpha-stereoisomer of 6-methylprednisolone.
Chemical ID: MESH:D008775
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1increases expressionISOCOL1A1 (Homo sapiens)6480464CTDMethylprednisolone results in increased expression of COL1A1 mRNAPMID:19192274
Col1a1multiple interactionsISOCol1a1 (Rattus norvegicus)6480464CTDMethylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]PMID:26093215
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