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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:18422
Term: sulfur dioxide
Definition: A sulfur oxide that has formula O2S.
Chemical ID: MESH:D013458
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8increases expressionEXP 6480464CTDSulfur Dioxide results in increased expression of CASP8 mRNAPMID:19621461 PMID:35533050
Casp8multiple interactionsEXP 6480464CTDSulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 proteinPMID:19621461 PMID:30503585
Casp8multiple interactionsISOCASP8 (Homo sapiens)6480464CTD[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNAPMID:31268311
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