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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620925
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1a
Name: PPARG coactivator 1 alpha
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1adecreases expressionISOPpargc1a (Mus musculus)6480464CTDnickel chloride results in decreased expression of PPARGC1A mRNA; nickel chloride results in decreased expression of PPARGC1A proteinPMID:38552765
Ppargc1amultiple interactionsISOPpargc1a (Mus musculus)6480464CTD[nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of PPARGC1A proteinPMID:36794572
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