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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620925
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1a
Name: PPARG coactivator 1 alpha
Acc ID: CHEBI:193350
Term: ferulic acid
Definition: A member of the class of ferulic acids that is cinnamic acid substituted by a methoxy and a hydroxy group at positions 3 and 4 of the phenyl ring.
Chemical ID: MESH:C004999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1amultiple interactionsEXP 6480464CTDferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]PMID:31029786
Ppargc1adecreases expressionISOPpargc1a (Mus musculus)6480464CTDferulic acid results in decreased expression of PPARGC1A mRNAPMID:30503583
Ppargc1amultiple interactionsISOPpargc1a (Mus musculus)6480464CTDferulic acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]PMID:30503583
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