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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620925
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1a
Name: PPARG coactivator 1 alpha
Acc ID: CHEBI:174690
Term: clenbuterol
Definition: A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.
Chemical ID: MESH:D002976
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1aincreases expressionEXP 6480464CTDClenbuterol results in increased expression of PPARGC1A mRNAPMID:17446185
Ppargc1aincreases expressionISOPpargc1a (Mus musculus)6480464CTDClenbuterol results in increased expression of PPARGC1A mRNAPMID:17446185
Ppargc1amultiple interactionsISOPpargc1a (Mus musculus)6480464CTDPropranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA]PMID:17446185
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