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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620897
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dusp1
Name: dual specificity phosphatase 1
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dusp1affects expressionEXP 6480464CTDCadmium Chloride affects the expression of DUSP1 mRNAPMID:22110744
Dusp1decreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of DUSP1 mRNAPMID:25993096
Dusp1increases methylationEXP 6480464CTDCadmium Chloride results in increased methylation of DUSP1 promoterPMID:22457795
Dusp1decreases expressionISODUSP1 (Homo sapiens)6480464CTDCadmium Chloride results in decreased expression of DUSP1 mRNAPMID:38568856
Dusp1multiple interactionsISODUSP1 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DUSP1 mRNAPMID:31738976
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