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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g2a
Name: phospholipase A2 group IIA
Acc ID: CHEBI:164200
Term: triclosan
Definition: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Chemical ID: MESH:D014260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g2aincreases expressionISOPLA2G2A (Homo sapiens)6480464CTDTriclosan results in increased expression of PLA2G2A mRNAPMID:30510588
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