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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g2a
Name: phospholipase A2 group IIA
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g2aincreases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of PLA2G2A mRNA; Lipopolysaccharides results in increased expression of PLA2G2A proteinPMID:21943492
Pla2g2amultiple interactionsEXP 6480464CTD[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PLA2G2A mRNA; [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PLA2G2A protein; IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of PLA2G2A protein]PMID:21943492
Pla2g2aincreases expressionISOPLA2G2A (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of PLA2G2A proteinPMID:15964894
Pla2g2aincreases expressionISOPla2g2a (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of PLA2G2A mRNAPMID:29248447
Pla2g2amultiple interactionsISOPLA2G2A (Homo sapiens)6480464CTD[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of PLA2G2A mRNAPMID:21878375
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