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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cflar
Name: CASP8 and FADD-like apoptosis regulator
Acc ID: CHEBI:16336
Term: hyaluronic acid
Definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.
Chemical ID: MESH:D006820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cflarmultiple interactionsISOCFLAR (Homo sapiens)6480464CTD[Diclofenac co-treated with Hyaluronic Acid] results in decreased expression of CFLAR proteinPMID:20237495
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