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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bnip3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bnip3affects expressionEXP 6480464CTDbisphenol A affects the expression of BNIP3 mRNAPMID:30903817
Bnip3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of BNIP3 mRNAPMID:30816183 PMID:32145629 PMID:34947998
Bnip3increases expressionEXP 6480464CTDbisphenol A results in increased expression of BNIP3 mRNAPMID:25181051 PMID:33296240
Bnip3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of BNIP3 genePMID:28505145
Bnip3affects expressionISOBNIP3 (Homo sapiens)6480464CTDbisphenol A affects the expression of BNIP3 mRNAPMID:30903817
Bnip3decreases expressionISOBNIP3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BNIP3 mRNAPMID:29275510
Bnip3decreases expressionISOBnip3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of BNIP3 mRNAPMID:33221593
Bnip3decreases methylationISOBNIP3 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of BNIP3 promoterPMID:30352284
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