GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl4 | increases expression | ISO | CCL4 (Homo sapiens) | 6480464 | CTD | Poly I-C results in increased expression of CCL4 mRNA | PMID:27783115 | Ccl4 | increases expression | ISO | Ccl4 (Mus musculus) | 6480464 | CTD | Poly I-C results in increased expression of CCL4 protein | PMID:19500611 | Ccl4 | increases secretion | ISO | Ccl4 (Mus musculus) | 6480464 | CTD | Poly I-C results in increased secretion of CCL4 protein | PMID:24056979 | Ccl4 | multiple interactions | ISO | CCL4 (Homo sapiens) | 6480464 | CTD | 6-formylindolo(3,2-b)carbazole inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA]; [TL8-506 co-treated with Poly I-C] results in increased expression of CCL4 mRNA; [TL8-506 co-treated with Poly I-C] results in increased secretion of CCL4 protein; Tetrachlorodibenzodioxin inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA] | PMID:27783115 PMID:35688559 | Ccl4 | multiple interactions | ISO | Ccl4 (Mus musculus) | 6480464 | CTD | Ethanol inhibits the reaction [Poly I-C results in increased expression of CCL4 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein] | PMID:19500611 PMID:24056979 | |
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