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GENE - TERM ANNOTATION REPORT

RGD ID: 620404
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adam17
Name: ADAM metallopeptidase domain 17
Acc ID: GO:0007173
Term: epidermal growth factor receptor signaling pathway
Definition: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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