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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620299
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ereg
Name: epiregulin
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eregincreases expression ISOEreg (Mus musculus)39457688RGDdextran sodium sulfate increases expression of Ereg protein in colonic mucosa 
Eregdecreases response to substanceISOEreg (Mus musculus)6480464CTDEREG protein results in decreased susceptibility to Dextran SulfatePMID:15456865
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