Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620190
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Becn1
Name: beclin 1
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Becn1increases expressionEXP 6480464CTDPalmitic Acid results in increased expression of BECN1 proteinPMID:34774660
Becn1decreases expressionISOBECN1 (Homo sapiens)6480464CTDPalmitic Acid results in decreased expression of BECN1 proteinPMID:30208301
Becn1decreases expressionISOBecn1 (Mus musculus)6480464CTDPalmitic Acid results in decreased expression of BECN1 proteinPMID:30208301
Becn1multiple interactionsISOBECN1 (Homo sapiens)6480464CTD[Palmitic Acid co-treated with Arsenic] affects the expression of BECN1 mRNA; BECN1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein]PMID:25943029 PMID:30208301 PMID:33736254
Becn1multiple interactionsISOBecn1 (Mus musculus)6480464CTDtrigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein]PMID:30208301
Go Back to source page   Continue to Ontology report