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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620144
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk1
Name: neurotrophic receptor tyrosine kinase 1
Acc ID: CHEBI:61048
Term: ganglioside GM1
Definition: A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.
Chemical ID: MESH:D005677
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk1multiple interactionsEXP 6480464CTDG(M1) Ganglioside inhibits the reaction [Methylmercury Compounds results in decreased phosphorylation of NTRK1 protein]; G(M1) Ganglioside inhibits the reaction [staurosporine aglycone results in decreased phosphorylation of NTRK1 protein]PMID:25545984
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