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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620144
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk1
Name: neurotrophic receptor tyrosine kinase 1
Acc ID: CHEBI:4745
Term: echinacoside
Definition: An oligosaccharide that has formula C35H46O20.
Chemical ID: MESH:C060297
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk1increases phosphorylationEXP 6480464CTDechinacoside results in increased phosphorylation of NTRK1 proteinPMID:23189969
Ntrk1multiple interactionsEXP 6480464CTDechinacoside inhibits the reaction [Rotenone results in decreased phosphorylation of NTRK1 protein]; staurosporine aglycone inhibits the reaction [echinacoside results in increased phosphorylation of NTRK1 protein]PMID:23189969
Ntrk1multiple interactionsISONTRK1 (Homo sapiens)6480464CTDechinacoside inhibits the reaction [Rotenone results in decreased phosphorylation of NTRK1 protein]; staurosporine aglycone inhibits the reaction [echinacoside inhibits the reaction [Rotenone results in decreased phosphorylation of NTRK1 protein]]PMID:23189969
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