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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620047
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:52392
Term: 2-arachidonoylglycerol
Definition: An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol.
Chemical ID: MESH:C094503
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2multiple interactionsISOIL2 (Homo sapiens)6480464CTDglyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]PMID:21511917
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