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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620047
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of IL2 proteinPMID:15603720
Il2multiple interactionsEXP 6480464CTDoxymatrine inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL2 protein]PMID:15603720
Il2decreases expressionISOIl2 (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased expression of IL2 proteinPMID:15133898
Il2increases expressionISOIl2 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of IL2 proteinPMID:17412915 PMID:29987408
Il2multiple interactionsISOIl2 (Mus musculus)6480464CTDPANX1 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL2 protein]PMID:29987408
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