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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:9546
Term: thimerosal
Definition: An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
Chemical ID: MESH:D013849
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases expressionISOVEGFA (Homo sapiens)6480464CTDThimerosal results in decreased expression of VEGFA mRNAPMID:27188386
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTD[Thimerosal co-treated with Temozolomide] results in decreased expression of VEGFA proteinPMID:38325586
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