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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619989
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ido1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: CHEBI:24814
Term: indole-3-methanol
Definition: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Chemical ID: MESH:C016517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ido1increases expressionISOIdo1 (Mus musculus)6480464CTDindole-3-carbinol results in increased expression of IDO1 mRNAPMID:21948866
Ido1multiple interactionsISOIdo1 (Mus musculus)6480464CTDLipopolysaccharides affects the susceptibility to [indole-3-carbinol results in increased expression of IDO1 mRNA]PMID:21948866
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