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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619989
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ido1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: CHEBI:18012
Term: fumaric acid
Definition: A butenedioic acid in which the C=C double bond has E geometry. It is an intermediate metabolite in the citric acid cycle.
Chemical ID: MESH:C032005
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ido1multiple interactionsISOIdo1 (Mus musculus)6480464CTDIDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of fumaric acid]PMID:39172838
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