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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:32270
Term: trospium chloride
Definition: An organic chloride salt of trospium. It is an antispasmodic drug used for the treatment of overactive bladder.
Chemical ID: MESH:C003330
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases transportISOABCB1 (Homo sapiens)6480464CTDABCB1 protein results in increased transport of trospium chloridePMID:25466967
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDvalspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride]PMID:25466967
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