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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619935
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Krt18
Name: keratin 18
Acc ID: CHEBI:10429
Term: beta-lapachone
Definition: A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
Chemical ID: MESH:C014638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Krt18increases expressionISOKRT18 (Homo sapiens)6480464CTDbeta-lapachone results in increased expression of KRT18 mRNAPMID:38218311
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