GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gch1 | increases abundance | ISO | Gch1 (Mus musculus) | 6480464 | CTD | GCH1 gene mutant form results in increased abundance of 7,8-dihydrobiopterin | PMID:25490417 | Gch1 | multiple interactions | ISO | Gch1 (Mus musculus) | 6480464 | CTD | [GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin; EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin] | PMID:25490417 | |
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