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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619871
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gclm
Name: glutamate cysteine ligase, modifier subunit
Acc ID: CHEBI:6872
Term: methylene blue
Definition: An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.
Chemical ID: MESH:D008751
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gclmmultiple interactionsISOGclm (Mus musculus)6480464CTD[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLM mRNAPMID:24556215
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