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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619823
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xrcc1
Name: X-ray repair cross complementing 1
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xrcc1decreases oxidationISOXrcc1 (Mus musculus)6480464CTDXRCC1 protein results in decreased oxidation of GlutathionePMID:30998386
Xrcc1increases oxidationISOXrcc1 (Mus musculus)6480464CTDXRCC1 gene mutant form results in increased oxidation of GlutathionePMID:30998386
Xrcc1multiple interactionsISOXrcc1 (Mus musculus)6480464CTDAcetylcysteine promotes the reaction [XRCC1 protein results in decreased oxidation of Glutathione]PMID:30998386
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