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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619795
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atrx
Name: ATRX, chromatin remodeler
Acc ID: CHEBI:50223
Term: (+)-dexrazoxane
Definition: A razoxane that has formula C11H16N4O4.
Chemical ID: MESH:D064730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atrxmultiple interactionsISOAtrx (Mus musculus)6480464CTD[Dexrazoxane co-treated with Idarubicin] results in increased expression of ATRX protein; Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of ATRX mRNA]PMID:28973540
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