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GENE - TERM ANNOTATION REPORT

RGD ID: 619758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grb2
Name: growth factor receptor bound protein 2
Acc ID: GO:0042552
Term: myelination
Definition: The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Definition Source(s): GOC:dgh, GOC:mah
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grb2involved_inISOGrb2 (Mus musculus)1624291RGDMGI:1929598 MGI:2177256 MGI:2448075 PMID:10704452 PMID:18760695

PMID:10704452 PMID:18760695
Grb2involved_inIEAUniProtKB:Q60631 or ensembl:ENSMUSP000000210901600115EnsemblGO_REF:0000107

GO_REF:0000107
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