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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rac1
Name: Rac family small GTPase 1
Acc ID: CHEBI:5959
Term: irbesartan
Definition: A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Chemical ID: MESH:C081309
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rac1multiple interactionsISORac1 (Mus musculus)6480464CTDCholesterol inhibits the reaction [irbesartan results in increased expression of RAC1 mRNA]PMID:19028402
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