GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rac1 | decreases response to substance | ISO | Rac1 (Mus musculus) | 6480464 | CTD | RAC1 gene mutant form results in decreased susceptibility to Asbestos, Serpentine | PMID:19684199 | Rac1 | increases activity | ISO | Rac1 (Mus musculus) | 6480464 | CTD | Asbestos, Serpentine results in increased activity of RAC1 protein | PMID:19684199 | Rac1 | multiple interactions | ISO | Rac1 (Mus musculus) | 6480464 | CTD | RAC1 protein affects the reaction [Asbestos, Serpentine results in increased expression of TNF mRNA]; RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein] | PMID:19684199 | Rac1 | multiple interactions | ISO | RAC1 (Homo sapiens) | 6480464 | CTD | RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein] | PMID:19684199 | | ||||||||||||||||||||||
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